For healthcare professionals only

Research Article

Idiopathic heart block: association with vitiligo, thyroid disease, pernicious anaemia, and diabetes mellitus.

Br Med J 1975; 4 doi: (Published 08 November 1975) Cite this as: Br Med J 1975;4:322
  1. A J Fairfax,
  2. A Leatham


    Out of 100 patients with chronic heart block 16 had one or more autoimmune disorders-namely, vitiligo (5,) hypothyroidism (4), Graves's disease (1), pernicious anaemia (2), and diabetes mellitus (9). All these disorders occurred with greater frequency than normal and were more prevalent than in a group of hospital inpatients of comparable age. Autoantibodies were not increased. We suggest that among patients with idiopathic heart block there is a subgroup with multiple autoimmune disorders.