Papers And Originals

Trigger factors and HL-A antigens in chronic active hepatitis

Br Med J 1975; 4 doi: (Published 11 October 1975) Cite this as: Br Med J 1975;4:77
  1. Johan Lindberg,
  2. Annika Lindholm,
  3. Per Lundin,
  4. Sten Iwarson


    Forty-six patients with histologically verified chronic active hepatitis (CAH) were divided into three groups according to whether the CAH was virus-induced, drug-induced, or cryptogenic. The frequency of the HL-A antigens 1 and 8 was increased in the cryptogenic group while the other groups did not differ significantly from healthy controls. Autoantibodies were often found in high titres in the drug-induced and cryptogenic groups but were infrequent in the virus-induced group.