Papers And Originals

Adrenergic, Coagulation, and Fibrinolytic Responses to Heat

Br Med J 1974; 4 doi: (Published 19 October 1974) Cite this as: Br Med J 1974;4:139
  1. B. J. Britton,
  2. Christine Hawkey,
  3. W. G. Wood,
  4. Muriel Peele,
  5. J. Kaye,
  6. M. H. Irving


    Two groups of volunteers were exposed to heat in a sauna bath—one group for 10 minutes and the other for 15. There was no change in plasma adrenaline concentration until the subjects emerged from the sauna bath, when there was a slight increase in concentration. Factor VIII and thrombo-elastograph patterns did not change but marked activation of fibrinolysis was stimulated by exposure to heat. These findings support the concept that fibrinolysis is not mediated by direct adrenergic activity.