Papers And Originals

Effect of a Millipore Filter on Complications of Intravenous Infusions: A Prospective Clinical Trial

Br Med J 1973; 4 doi: (Published 24 November 1973) Cite this as: Br Med J 1973;4:456
  1. J. Collin,
  2. D. E. F. Tweedle,
  3. C. W. Venables,
  4. F. L. Constable,
  5. Ivan D. A. Johnston


    The Millipore filter unit has been advocated as a means of reducing the chance of bacteria entering the circulation during intravenous infusion. In a prospective study no significant reduction was obtained in the incidence of thrombophlebitis or in the bacterial contamination of cannulae. The unit was inconvenient to use and in-vitro and in-vivo studies showed reduced flow rates and frequent episodes of filter blockage. Its use was further restricted by the fact that blood and fat emulsions would not pass through it.