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Rapid Microbiological Assay for 5-Fluorocytosine

Br Med J 1973; 4 doi: (Published 17 November 1973) Cite this as: Br Med J 1973;4:380
  1. D. J. Schiavone,
  2. M. D. Page,
  3. J. K. Dawborn


    A microbiological assay was developed for 5-fluorocytosine based on inhibition by the drug of the fall in pH produced by Candida albicans in a synthetic liquid culture medium. Serum and urine levels of the drug could be measured reproducibly in four hours.