Papers And Originals

Prostaglandin 15 (R) 15-methyl-E2 Methyl Ester for Suppression of Gastric Acidity in Gravida at Term

Br Med J 1973; 4 doi: (Published 27 October 1973) Cite this as: Br Med J 1973;4:208
  1. J. J. Amy,
  2. D. M. Jackson,
  3. P. Adaikan Ganesan,
  4. S. M. M. Karim


    During the second hour after giving 100 μg of orally administered prostaglandin 15 (R) 15-methyl-E2 methyl ester in the pregnant patient at term a noticeable reduction in basal gastric acid secretion took place. At this dose no excessive uterine stimulation was observed. Prostaglandin 15 (R) 15-methyl-E2 methyl ester could prove of value in the preoperative preparation of the pregnant patient before anaesthesia for reducing the incidence of acid regurgitation.