Papers And Originals

Interference of Iron with the Absorption of Tetracylines in Man

Br Med J 1970; 4 doi: (Published 28 November 1970) Cite this as: Br Med J 1970;4:532
  1. P. J. Neuvonen,
  2. G. Gothoni,
  3. R. Hackman,
  4. K. af Björksten


    Ferrous sulphate administered together with tetracycline and three of its derivatives—oxytetracycline, methacycline, and doxycycline—was found seriously to impair the absorption of these antibiotics. Thus even small doses of iron taken simultaneously should be avoided during tetracycline treatment.