Papers And Originals

Interrelationships of blood sugar and ketones in insulin-treated diabetics

Br Med J 1969; 4 doi: (Published 13 December 1969) Cite this as: Br Med J 1969;4:648
  1. P. J. Watkins,
  2. M. G. FitzGerald,
  3. J. M. Malins


    A survey of ketonuria in insulin-treated diabetics showed that its significance might vary according to the time of day at which the test was performed. Some of the patients had uncontrolled diabetes in the early morning, when severe hyperglycaemia and hyperketonaemia occurred together, while later during the same day or night an episode of hypoglycaemia caused hyperketonaemia, indicating that too much insulin had been given. Correct assessment of the significance of ketonuria is obviously important, because some patients would probably require a decrease rather than an increase of insulin dosage. Ketonuria does not necessarily indicate impending ketoacidosis.


    • * This work forms part of the dissertation for the Cambridge M.D. degree of P. J. Watkins.