Papers And Originals

Remission induction with cytosine arabinoside and L-Asparaginase in acute lymphoblastic leukaemia

Br Med J 1969; 4 doi: (Published 06 December 1969) Cite this as: Br Med J 1969;4:596
  1. T. J. McElwain,
  2. R. M. Hardisty


    Nine patients with acute lymphoblastic leukaemia in relapse were treated with a course of cytosine arabinoside followed immediately by a course of L-asparaginase. Eight patients achieved complete remission of their disease. This combination of drugs is sufficiently effective to suggest that further trial is needed. It is possible that the combination has a synergistic effect.