Intended for healthcare professionals


NHS to match blood genetically for people with sickle cell and thalassemia in England

BMJ 2023; 381 doi: (Published 24 May 2023) Cite this as: BMJ 2023;381:p1204
  1. Elisabeth Mahase
  1. The BMJ

The NHS in England will soon introduce a new genetic blood matching test for people with sickle cell disease or thalassemia to match transfusions to patients better and reduce painful side effects.

Although blood is currently matched by blood group, differences within blood groups can trigger immune responses to transfused blood cells in just under a fifth (17%) of patients, leading to side effects.

To reduce these reactions, NHS …

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