Intended for healthcare professionals

Minerva

Bacterial indicators . . . and other stories

BMJ 2023; 381 doi: https://doi.org/10.1136/bmj.p1126 (Published 25 May 2023) Cite this as: BMJ 2023;381:p1126

Rheumatoid arthritis and the gut microbiome

Fusobacterium nucleatum is a common anaerobic organism implicated in periodontal disease and colorectal cancer. It’s present in abundance in stool samples from people with rheumatoid arthritis, and bacterial numbers correlate with severity of disease. What’s more, F nucleatum exacerbated arthritis in a mouse model, by triggering the production of inflammatory mediators and activating synovial macrophages (Cell Host Microbe doi:10.1016/j.chom.2023.03.018).

Mediterranean diets

A score based on plasma carotenoid and fatty acid concentrations has been developed as a biomarker for adherence to a Mediterranean diet. Tested in 22 000 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) study, this score was related to the incidence of type …

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