Intended for healthcare professionals

Letters Reducing unnecessary use of proton pump inhibitors

Objective testing is useful to support PPI deprescribing

BMJ 2022; 379 doi: https://doi.org/10.1136/bmj.o2812 (Published 23 November 2022) Cite this as: BMJ 2022;379:o2812
  1. Ian L P Beales, consultant gastroenterologist
  1. Norfolk and Norwich University Hospital, Norwich, UK
  1. i.beales{at}uea.ac.uk

Proton pump inhibitors (PPIs) are overused. Farrell and colleagues have outlined useful ways to approach deprescribing.1

Putative gastro-oesophageal reflux disease probably accounts for a large proportion of long term PPI prescribing. The clinical diagnosis of gastro-oesophageal reflux disease is notoriously unreliable and upper gastrointestinal endoscopy yields normal results in at least 50% of patients with pathological reflux—more if …

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