Re: Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort
Caffeine may lower the risk of stroke. Caffeine is a very common additive in sweetener containing beverages. Was caffeine analysed as a confounding or mitigating variable is this study, the financial consequence of which could be very large? It is possible that caffeine may interact differently with the eight different sweeteners listed.
Reference: Zhang Y, Yang H, Li S, Wang Y. Consumption of coffee and tea and risk of developing stroke, dementia or poststroke dementia: a cohort study in the UK Biobank. PLOS Medicine https://doi.org/10.1371/journal.pmed.1003830
Competing interests: No competing interests