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Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort

BMJ 2022; 378 doi: https://doi.org/10.1136/bmj-2022-071204 (Published 07 September 2022) Cite this as: BMJ 2022;378:e071204

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Re: Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort

Dear Editor
Caffeine may lower the risk of stroke. Caffeine is a very common additive in sweetener containing beverages. Was caffeine analysed as a confounding or mitigating variable is this study, the financial consequence of which could be very large? It is possible that caffeine may interact differently with the eight different sweeteners listed.

Reference: Zhang Y, Yang H, Li S, Wang Y. Consumption of coffee and tea and risk of developing stroke, dementia or poststroke dementia: a cohort study in the UK Biobank. PLOS Medicine https://doi.org/10.1371/journal.pmed.1003830

Competing interests: No competing interests

09 September 2022
William P. Tormey
Medical doctor and Journal editor
Royal Academy of Medicine in Ireland
Royal academy of Medicine in Ireland. Kildare St, Dublin 2