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Minerva

Interventions for mild hyperparathyroidism . . . and other stories

BMJ 2022; 377 doi: https://doi.org/10.1136/bmj.o1467 (Published 23 June 2022) Cite this as: BMJ 2022;377:o1467

Surgery for primary hyperparathyroidism

Primary hyperparathyroidism raises the risk of bony fractures, cardiovascular disease, kidney disease, and cancer. But is the increase large enough to justify surgical intervention in people with mild forms of the disease and modest degrees of hypercalcaemia? Probably not, according to the results of a long running randomised controlled trial from eight Scandinavian centres. Among patients allocated to surgery, outcomes during an extended period of follow-up were similar to those who had been allocated to observation alone (Ann Intern Med doi:10.7326/M21-4416).

Optimism and longevity

Perhaps it’s not surprising that people with an optimistic outlook on life live longer than those with a less sunny disposition. What …

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