Intended for healthcare professionals


Update to living systematic review on covid-19 in pregnancy

BMJ 2022; 377 doi: (Published 30 May 2022) Cite this as: BMJ 2022;377:o1205

This living systematic review on coronavirus disease 2019 (covid-19) by Allotey and colleagues (BMJ 2020;370:m3320) has been updated. For the latest update, visit doi:10.1136/bmj.m3320. This second update includes 435 studies (293 152 pregnant and recently pregnant women with covid-19), of which 244 were new additions to the review. The prevalence of covid-19 in pregnant and recently pregnant women remain consistent with our original review and first update of the living systematic review. Pregnant women continue to be at increased risk of severe covid-19. In addition to high body mass index, advancing maternal age, and non-white ethnic origin, evidence suggests that pre-existing comorbidities, and pregnancy specific conditions such as pre-eclampsia and gestational diabetes are risk factors for severe disease. More data are needed to robustly assess the association between pregnancy specific conditions and covid-19 related outcomes.