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Lancet will not retract discredited paper on tissue engineered trachea transplants

BMJ 2022; 376 doi: https://doi.org/10.1136/bmj.o600 (Published 07 March 2022) Cite this as: BMJ 2022;376:o600
  1. Ingrid Torjesen
  1. The BMJ

The Lancet has said that it will not retract a 2008 paper on tissue engineered trachea transplants, despite concerns about the conduct and validity of the research raised in a letter to The BMJ.1

The 2008 paper, involving researchers from Hospital Clinic Barcelona, Karolinska Institutet, and UCL, reported that transplant of a human cadaveric trachea, decellularised and colonised with stem cells from the recipient, “immediately provided the recipient with a functional airway, improved her quality of life, and had a normal appearance and mechanical properties at four months.”2

The paper’s lead author Paolo Macchiarini was sacked by the Karolinska Institutet;3 found guilty …

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