Vitamin D supplements . . . and other stories
BMJ 2022; 376 doi: https://doi.org/10.1136/bmj.o452 (Published 03 March 2022) Cite this as: BMJ 2022;376:o452
Vitamin D and mortality in older people
In 2014, a Cochrane review concluded that Vitamin D3 supplements might reduce mortality in older people and recommended further trials (Cochrane Database Syst Rev doi:10.1002/14651858.CD007470.pub3). A randomised controlled trial of oral vitamin D3 supplementation for five years in Australians aged 60 or older reports no benefits. Among 20 000 participants followed for five years, the primary outcome—death from any cause—occurred as frequently in those taking the active supplement as it did in those taking placebo (Lancet Diabetes Endocrinol doi:10.1016/S2213-8587(21)00345-4).
Subclinical hypothyroidism
Defined as a thyroid stimulating hormone concentration higher than the reference range with normal free thyroxine …
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