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Covid-19: AstraZeneca vaccine is not linked to increased risk of blood clots, finds European Medicine Agency

BMJ 2021; 372 doi: (Published 19 March 2021) Cite this as: BMJ 2021;372:n774

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Role of Testing for ADAMTS13 enzyme deficiency in patients with clots after Covid-19 infection and/or AstraZeneca vaccine.

Dear Editor,

Listening to the recent data on the rare but evolving probable correlation between clots and vaccine, I would like to know whether the patients with the clots have been tested for their ADAMTS13 enzyme assay? Could there be any inherent or acquired enzyme deficiency, due to ?autoantibodies to the enzyme as has been seen with Thrombotic Thrombocytopenic Purpura? In addition, was plasma exchange offered to these patients in intensive care?

I look forward to your response.

Thank you

Dr. Ruchi Arora

Competing interests: No competing interests

07 April 2021
Ruchi Arora
Consultant Paediatrician
Norfolk and Norwich University Hospital
JENNY Lind children's hospital, NNUH