Intended for healthcare professionals


Seven days in medicine: 3-9 February 2021

BMJ 2021; 372 doi: (Published 11 February 2021) Cite this as: BMJ 2021;372:n374


Four in 10 with past infection had no classic symptoms

Around a quarter of people with evidence of past covid-19 infection were completely asymptomatic, a UK study found, while 40% did not have any of the three classic symptoms of fever, persistent dry cough, or loss of taste or smell. The UK Biobank SARS-CoV-2 Serology study analysed monthly blood samples of nearly 19 000 people from 27 May to 4 December 2020. Some 99% of participants who tested positive for previous infection retained antibodies for three months after being infected, and 88% did so for at least six months. (Full story doi:10.1136/bmj.n321)

Oxford vaccine data support 12 week dose interval

The UK’s approach of leaving a three month interval between doses of the Oxford-AstraZeneca covid-19 vaccine was backed by new data, and Oxford University researchers said that the vaccine “may have a substantial impact on transmission.” The paper, a preprint under review by the Lancet, is an analysis of additional data from trials involving 17 177 participants in the UK, Brazil, and South Africa. A single standard dose of vaccine provided 76% protection overall against symptomatic covid-19 in the first 90 days after vaccination, and protection did not wane in that time frame. (Full story doi:10.1136/bmj.n326)

Russian vaccine efficacy is 91.6%, results show

The covid-19 vaccine developed by …

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