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Rapid response to:


Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study

BMJ 2021; 372 doi: (Published 11 February 2021) Cite this as: BMJ 2021;372:n311

Linked Editorial

Prophylactic anticoagulation for patients in hospital with covid-19

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Rapid Response:

Re: prophylactic and therapeutic anticoagulation for prevention of CoVID19

Dear Editor

Does the reduction in the risk of mortality and the initiation of therapeutic anticoagulation indicate that early administration of LMW heparin is required as clotting is a cascade?? This is also suggested by the results of the large international clinical trials on prophylactic vs therapeutic doses of anticoagulant which are currently being finalized (

Competing interests: No competing interests

14 February 2021
camilo A colaco
Cell Therapy Laboratories, CUH NHS Foundation Trust