Biomarkers for vascular disease . . . and other stories
BMJ 2020; 370 doi: https://doi.org/10.1136/bmj.m3401 (Published 10 September 2020) Cite this as: BMJ 2020;370:m3401New biomarkers in coronary artery disease
Several novel circulating biomarkers for vascular disease have emerged recently. Examples are neutrophil gelatinase-associated lipocalin, osteoprotegerin, endostatin, YKL40, and cathepsin-B. Although individually they showed associations with heart disease and all-cause mortality, they contributed disappointingly little to the predictive value of conventional risk factors. In patients with stable coronary artery disease, the addition of data on 10 new biomarkers improved the accuracy of the prediction model by less than 2% (BMJ Open doi:10.1136/bmjopen-2019-033720).
Vaccine design
More than a hundred vaccines against SARS-CoV-2 are currently in development using a variety of technologies, some …
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