Intended for healthcare professionals


Myocardial infarction at night . . . and other stories

BMJ 2020; 369 doi: (Published 28 May 2020) Cite this as: BMJ 2020;369:m2036

Timing of myocardial infarction

An early morning peak in the incidence of ST-segment elevation myocardial infarction is well known, even if the reasons for it are obscure. A registry study from Singapore finds that timing has an influence on long term outcomes. People whose symptoms began in the evening or during the night were roughly 50% more likely to require hospitalisation for heart failure in the year following the infarction (Am Heart J doi:10.1016/j.ahj.2020.03.011). Duration of ischaemia before treatment may be the explanation.

Diabetes and osteoarthritis

Reports of a positive association between diabetes and osteoarthritis are hard to interpret because being overweight or obese strongly increases the risk of both conditions. A systematic review that identified 31 studies with a total of nearly 300 000 participants reckons that if body mass index is taken into account, there’s little evidence that diabetes is a cause of osteoarthritis (RMD Open doi:10.1136/rmdopen-2019-001030). Comparing …

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