Intended for healthcare professionals

  1. Research
  2. Features of 20 133 UK...
  3. Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study
CCBY Open access
Research

Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study

BMJ 2020; 369 doi: https://doi.org/10.1136/bmj.m1985 (Published 22 May 2020) Cite this as: BMJ 2020;369:m1985

Linked Editorial

Covid-19 care before, during, and beyond the hospital

Read our latest coverage of the coronavirus pandemic

Data supplement

  • Web extra

    • Data Supplement - Web appendix: Supplementary material 1â€"online supplement
    • Data Supplement - Web appendix: Supplementary material 2â€"protocol
    • Data Supplement - Web appendix: Supplementary material 3â€"case report form

Related articles

EditorialCovid-19 care before, during, and beyond the hospital

See more

Cited by...

  • Serological responses to SARS-CoV-2 following non-hospitalised infection: clinical and ethnodemographic features associated with the magnitude of the antibody response
  • Association of Initial Clinical Characteristics with the Need for the Intensive Care Unit and Hospitalization in Patients Presenting to the Emergency Department with Acute Symptomatic COVID-19
  • Genetically diverse mouse models of SARS-CoV-2 infection model clinical variation and cytokine responses in COVID-19
  • Comparison of children and young people admitted with SARS-CoV-2 across the UK in the first and second pandemic waves: prospective multicentre observational cohort study
  • Interplay between the Genetics of Personality Traits, severe Psychiatric Disorders, and COVID-19 Host Genetics in the Susceptibility to SARS-CoV-2 Infection
  • COVID outcome prediction in the emergency department (COPE): using retrospective Dutch hospital data to develop simple and valid models for predicting mortality and need for intensive care unit admission in patients who present at the emergency department with suspected COVID-19
  • COVID-19 in older adults
  • The 1st year of the COVID-19 epidemic in Estonia: an interrupted time series of population based nationwide cross-sectional studies
  • COVID-19 pneumothorax in the UK: a prospective observational study using the ISARIC WHO clinical characterisation protocol
  • CPAP delivered outside critical care during the second wave of COVID-19: outcomes from a UK respiratory surge unit
  • HLA-B*15:01 is associated with asymptomatic SARS-CoV-2 infection
  • The contribution of hospital-acquired infections to the COVID-19 epidemic in England in the first half of 2020
  • Cigarette smoke preferentially induces full length ACE2 exposure in primary human airway cells but does not alter susceptibility to SARS-CoV-2 infection
  • Long-term corticosteroid therapy for patients with severe coronavirus disease 2019 (COVID-19)
  • External validation of the 4C Mortality Score for patients with COVID-19 and pre-existing cardiovascular diseases/risk factors
  • Functional respiratory capacity in the elderly after COVID-19 - a pilot study
  • Diarrhoea and preadmission antibiotic exposure in COVID-19: a retrospective cohort study of 1153 hospitalised patients
  • Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource
  • The effect of immunosuppressants on the prognosis of SARS-CoV-2 infection
  • Impact of COVID-19 lockdown on emergency asthma admissions and deaths: national interrupted time series analyses for Scotland and Wales
  • Impact of COVID-19 national lockdown on asthma exacerbations: interrupted time-series analysis of English primary care data
  • Development and validation of a prediction model for 30-day mortality in hospitalised patients with COVID-19: the COVID-19 SEIMC score
  • Excess Mortality in a Nationwide Cohort of Cancer Patients during the Initial Phase of the COVID-19 Pandemic in Belgium
  • External validation of 4C ISARIC mortality score in the setting of a Saudi Arabian ICU. Retrospective study
  • Association of body mass index with morbidity in patients hospitalised with COVID-19
  • Immuno-proteomic profiling reveals abundant airway CD8 T cells and ongoing epithelial injury in prolonged post-COVID19 respiratory disease
  • Impairment of T cells antiviral and anti-inflammation immunities dominates death from COVID-19
  • Ethnic and social inequalities in COVID-19 outcomes in Scotland: protocol for early pandemic evaluation and enhanced surveillance of COVID-19 (EAVE II)
  • Patients with idiopathic pulmonary fibrosis have poor clinical outcomes with COVID-19 disease: a propensity matched multicentre research network analysis
  • Combined association of obesity and other cardiometabolic diseases with severe COVID-19 outcomes: a nationwide cross-sectional study of 21 773 Brazilian adult and elderly inpatients
  • Increasing Numbers of Non-communicable Disease Co-morbidities: Major Risk Factors for Hospitalization among a Cohort of People with HIV and COVID-19 Coinfection
  • An adaptive randomized controlled trial of non-invasive respiratory strategies in acute respiratory failure patients with COVID-19
  • Clinical patterns, recovery time and prolonged impact of COVID-19 illness in international athletes: the UK experience
  • Age-specific rate of severe and critical SARS-CoV-2 infections estimated with multi-country seroprevalence studies
  • Lung Ultrasound Score to Predict Outcomes in COVID-19
  • Fitting to the UK COVID-19 outbreak, short-term forecasts and estimating the reproductive number
  • A decision-tree approach to treat platelet hyperactivity and anomalous blood clotting in acute COVID-19 patients
  • Plasma cell-free DNA promise disease monitoring and tissue injury assessment of COVID-19
  • Burden of nosocomial COVID-19 in Wales: results from a multicentre retrospective observational study of 2508 hospitalised adults
  • Using Population Based Kalman Estimator to Model COVID-19 Epidemic in France: Estimating the Effects of Non-Pharmaceutical Interventions on the Dynamics of Epidemic
  • Global and regional prevalence and outcomes of COVID-19 in people living with HIV: A cutting-edge systematic review and meta-analysis
  • Key epidemiological drivers and impact of interventions in the 2020 SARS-CoV-2 epidemic in England
  • Pandemic trends in health care use: From the hospital bed to the general practitioner with COVID-19
  • SARS-CoV-2 environmental contamination from hospitalised COVID-19 patients receiving aerosol generating procedures
  • Deaths in Children and Young People in England following SARS-CoV-2 infection during the first pandemic year: a national study using linked mandatory child death reporting data
  • Predictors of hospitalisation and death due to SARS-CoV-2 infection in Finland: a population-based register study with implications to vaccinations
  • Clinical presentation, disease course and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease - a cohort study across eighteen countries
  • Risk factors for SARS-CoV-2 infection and hospitalisation in children and adolescents in Norway: A nationwide population-based study
  • Patient-level and hospital-level variation and related time trends in COVID-19 case fatality rates during the first pandemic wave in England: multilevel modelling analysis of routine data
  • Clinical phenotypes and outcomes of SARS-CoV-2, influenza, RSV and seven other respiratory viruses: a retrospective study using complete hospital data
  • A national cohort study of COVID-19 in-hospital mortality in South Africa: the intersection of communicable and non-communicable chronic diseases in a high HIV prevalence setting
  • Post-COVID symptoms reported at asynchronous virtual review and stratified follow-up after COVID-19 pneumonia
  • Reduced survival after upper gastrointestinal bleed endoscopy in the COVID-19 era is a secondary effect of the response to the global pandemic: a retrospective cohort study
  • Current smoking and COVID-19 risk: results from a population symptom app in over 2.4 million people
  • Factors associated with COVID-19-related death in people with rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance physician-reported registry
  • United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers (UK-REACH): a retrospective cohort study using linked routinely collected data, study protocol
  • Age-related heterogeneity in immune responses to SARS-CoV-2 vaccine BNT162b2
  • Recovery from Covid-19 critical illness: a secondary analysis of the ISARIC4C CCP-UK cohort study and the RECOVER trial
  • Increased Risk of Severe COVID-19 Disease in Pregnancy in a Multicenter Propensity Score-Matched Study
  • Evaluation of the effectiveness of remdesivir in treating severe COVID-19 using data from the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, national cohort study
  • COVID-19 Outcomes and Genomic characterization of SARS-CoV-2 isolated from Veterans in New England States
  • Platform Randomised trial of INterventions against COVID-19 In older peoPLE (PRINCIPLE): protocol for a randomised, controlled, open-label, adaptive platform, trial of community treatment of COVID-19 syndromic illness in people at higher risk
  • Epidemiological and clinical characteristics of non-severe and severe pediatric and adult COVID-19 patients across different geographical regions in the early phase of pandemic: a systematic review and meta-analysis of observational studies
  • SARS-CoV-2 infection in pregnancy in Denmark - characteristics and outcomes after confirmed infection in pregnancy: a nationwide, prospective, population-based cohort study
  • Cardiovascular vulnerability predicts hospitalisation in primary care clinically suspected and confirmed COVID-19 patients: a model development and validation study
  • Caracteristiques et issues des hospitalisations pour les cas de COVID-19 et dinfluenza dans la region de Toronto
  • Occupational inequalities in the prevalence of COVID-19: A longitudinal observational study of England, August 2020 to January 2021
  • The isolated effect of age on the risk of COVID-19 severe outcomes: a systematic review with meta-analysis
  • Necrotising myopathy and concurrent thyroiditis in a patient with COVID-19 infection
  • Shift work is associated with positive COVID-19 status in hospitalised patients
  • Psychological distress during the acceleration phase of the COVID-19 pandemic: a survey of doctors practising in emergency medicine, anaesthesia and intensive care medicine in the UK and Ireland
  • Risk factors associated with severe outcomes of COVID-19: An updated rapid review to inform national guidance on vaccine prioritization in Canada
  • COVID-19 gender difference pattern in Iranian population compared to the global pattern; a systematic review and meta-analysis
  • Combined association of obesity and other cardiometabolic diseases with severe COVID-19 outcomes: a nationwide cross-sectional study of 21,773 Brazilian adult and elderly inpatients
  • Risk of clinical sequelae after the acute phase of SARS-CoV-2 infection: retrospective cohort study
  • COVID-19 pandemic experiences of parents caring for children with oesophageal atresia/tracheo-oesophageal fistula
  • Risk factors for severity of COVID-19: a rapid review to inform vaccine prioritisation in Canada
  • Mapping the human genetic architecture of COVID-19 by worldwide meta-analysis
  • Impact of National and Regional Lockdowns on Growth of COVID-19 Cases in COVID-Hotspot City of Pune in Western India: A Real-World Data Analysis
  • Infants are more susceptible to COVID-19 than children
  • Does the elevated (thrombosis risk of males relative to females help account for the excess male mortality observed in Covid-19? An observational study
  • Cost-effectiveness of COVID-19 vaccination in low- and middle-income countries
  • Decitabine Reactivation of FoxM1-Dependent Endothelial Regeneration and Vascular Repair for Potential Treatment of Elderly ARDS and COVID-19 Patients
  • 'Face time for the first time: Video communication between relatives and junior doctors in the COVID-19 pandemic
Back to top