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Blood markers to diagnose Parkinson’s . . . and other stories

BMJ 2019; 367 doi: https://doi.org/10.1136/bmj.l6387 (Published 14 November 2019) Cite this as: BMJ 2019;367:l6387

Biomarkers for Parkinson’s disease

Screening 1000 different proteins in blood samples from people with Parkinson’s disease and controls identified 10 candidate biomarkers for the disease. Four of these markers—bone sialoprotein, osteomodulin, aminoacylase-1, and growth hormone receptor—were also able to distinguish between people with Parkinson’s disease and controls in a second round of testing in another group of people (PLoS Med doi:10.1371/journal.pmed.1002931). The investigators hope that it will be possible to develop a blood based diagnostic test.

Postural hypotension in Parkinson’s disease

Talking of Parkinson’s disease, a longitudinal study from Norway finds that postural hypotension is common in people newly diagnosed with the …

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