Intended for healthcare professionals


NICE updates antidepressant guidelines to reflect severity and length of withdrawal symptoms

BMJ 2019; 367 doi: (Published 18 October 2019) Cite this as: BMJ 2019;367:l6103
  1. Gareth Iacobucci
  1. The BMJ

The National Institute for Health and Care Excellence has amended its guidelines1 on depression to recognise the severity and length of antidepressant withdrawal symptoms.

The guidance on treating depression in adults now states that withdrawal symptoms may be severe and protracted in some patients.

NICE’s previous guideline, which was originally published in 2009 and updated last year, said that withdrawal symptoms are “usually mild and self limiting over about one week.”2

But in an amendment, NICE acknowledges that …

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