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C reactive protein testing in general practice safely reduces antibiotic use for flare-ups of COPD

BMJ 2019; 367 doi: https://doi.org/10.1136/bmj.l5991 (Published 30 December 2019) Cite this as: BMJ 2019;367:l5991

Editorial

NIHR’s research signals in The BMJ
  1. Rob Cook, clinical director1,
  2. Johnny Lyon-Maris, clinical adviser2,
  3. Alicia White, analyst manager1
  4. on behalf of NIHR Dissemination Centre
  1. 1Bazian, Economist Intelligence Unit healthcare, London, UK
  2. 2Wessex Institute, University of Southampton, Southampton, UK
  1. Correspondence to R Cook rob.cook{at}bazian.com

The study

Butler CC, Gillespie D, White P, et al. C-reactive protein testing to guide antibiotic prescribing for COPD exacerbations. N Engl J Med 2019;381:111-20.

This research was funded by the NIHR Technology Assessment Programme (project number 12/33/12). The testing machines used in the study were loaned to researchers by the manufacturer, who also provided training on their use. The manufacturer had no other role in any part of the trial.

To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000820/crp-testing-safely-reduces-antibiotic-use-for-copd-flare-ups

Footnotes

  • Contributor: Hannah Spring.

  • All authors contributed to development and review of this summary, as part of the wider NIHR Signals editorial team. RC is guarantor.

  • Disclaimer NIHR Signals are owned by the Department of Health and Social Care and are made available to the BMJ under licence. NIHR Signals report and comment on health and social care research but do not offer any endorsement of the research. The NIHR assumes no responsibility or liability arising from any error or omission or from the use of any information contained in NIHR Signals.

  • Permission to reuse these articles should be directed to disseminationcentre@nihr.ac.uk.

  • Competing interestsThe BMJ has judged that there are no disqualifying financial ties to commercial companies. The authors declare the following other interests: none

  • Further details of The BMJ policy on financial interests is here: https://www.bmj.com/about-bmj/resources-authors/forms-policies-and-checklists/declaration-competing-interests

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