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  1. Education
  2. Levetiracetam is a...
  3. Levetiracetam is a useful alternative to phenytoin for epileptic seizures in children
Practice NIHR Signals

Levetiracetam is a useful alternative to phenytoin for epileptic seizures in children

BMJ 2019; 367 doi: https://doi.org/10.1136/bmj.l5464 (Published 11 November 2019) Cite this as: BMJ 2019;367:l5464

Editorial

NIHR’s research signals in The BMJ
  1. Rob Cook, clinical director1,
  2. Peter Davidson, clinical advisor 2,
  3. Rosie Martin, clinical specialist1
  4. on behalf of NIHR Dissemination Centre
  1. 1Bazian, Economist Intelligence Unit Healthcare, London, UK
  2. 2Wessex Institute, University of Southampton, Southampton, UK
  1. Correspondence to R Cook rob.cook{at}bazian.com

The study

Lyttle MD, Rainford NEA, Gamble C, et al. Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial. Lancet 2019;393:2125-34.

This trial was funded by the NIHR Health Technology Assessment Programme (project number 12/127/134).

To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000790/levetiracetam-vs-phenytoin-in-stopping-childrens-prolonged-epileptic-seizures

Footnotes

  • Contributor: Joelle Kirby

  • All authors contributed to development and review of this summary, as part of the wider NIHR Signals editorial team. RC is guarantor.

  • Disclaimer NIHR Signals are owned by the Department of Health and Social Care and are made available to the BMJ under licence. NIHR Signals report and comment on health and social care research but do not offer any endorsement of the research. The NIHR assumes no responsibility or liability arising from any error or omission or from the use of any information contained in NIHR Signals.

  • Permission to reuse these articles should be directed to disseminationcentre@nihr.ac.uk.

  • Competing interests The BMJ has judged that there are no disqualifying financial ties to commercial companies. The authors declare the following other interests: none

  • Further details of The BMJ policy on financial interests is here: https://www.bmj.com/about-bmj/resources-authors/forms-policies-and-checklists/declaration-competing-interests

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