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Readers of this article should be aware that the Health Product Profile Directory (https://www.who.int/tdr/diseases-topics/product-directory/en/) is a free-to-use online resource created and developed by TDR on behalf of WHO as a global public good to improve the efficiency of efforts to develop new products for neglected diseases and populations as well as threats to global health. It provides a searchable database of the 8-10 key characteristics used to describe desired health products, including medicines, vaccines, diagnostics and medical equipment. Links are provided to access the full Product Profile document where this is publicly available. The Directory was launched in May 2019 and will be continuously updated. Users should read the FAQ and user instructions document for full background information.