Polypill cuts major cardiovascular events by a third, study finds
BMJ 2019; 366 doi: https://doi.org/10.1136/bmj.l5268 (Published 22 August 2019) Cite this as: BMJ 2019;366:l5268- Stijntje Dijk,
- Pat Lok
- The BMJ
A once daily, low cost polypill combining four cardiovascular drugs reduced the risk of major cardiovascular events by a third over a five year period when compared with lifestyle advice, a large study has found.1
Poor adherence is particularly common among patients with cardiovascular disease, as previous studies suggest that around a third of patients stop taking their medicine as early as 90 days after a myocardial infarction.2
The concept of a polypill was first proposed over 15 years ago as a simple, cost saving approach to improve medicine adherence and reduce the burden of cardiovascular disease.3 But …
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