Re: Could giving statins to over 75s really save 8000 lives a year?
The short answer is no - but the media hype fails to point out, as Hawkes has done, that the figure appears to have been given in a press conference by a statin proponent and did not appear in the paper; it was a crude extrapolation from the conclusion.
However. as has been pointed out (1) the (limited) data available for other cardiac risk factors (smoking, alcohol misuse, diabetes and hypertension) appear to indicate that the high risk group has a higher incidence - but correction for these has not been done. Information on other risk factors such as obesity and exercise is non-existent.
Without adjustment for these important confounders the paper and its conclusions - not to mention extrapolations - are completely useless.
1. Harcombe Z. Statins don’t work well for half those who take them. http://www.zoeharcombe.com/2019/04/statins-dont-work-well-for-half-those...
Competing interests: I am a member of the International Network of Cholesterol Skeptics (THINCS)