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Letters High sensitivity cardiac troponin assay

High sensitivity troponin assays: too much of a good thing

BMJ 2019; 365 doi: https://doi.org/10.1136/bmj.l1640 (Published 16 April 2019) Cite this as: BMJ 2019;365:l1640
  1. Santhanam Sundar, consultant oncologist
  1. Nottingham University Hospital NHS Trust, Nottingham, UK
  1. sundar{at}oncology.org

When conventional troponin testing was introduced it helped rapid, accurate diagnosis or exclusion of myocardial infarction. The high predictive value of conventional assays enabled rapid discharge of patients presenting to emergency departments. But the newer high sensitivity troponin assays have inevitably traded specificity for sensitivity in …

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