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Minerva

Childhood radiotherapy, skin cancers . . . and other stories

BMJ 2019; 365 doi: https://doi.org/10.1136/bmj.l1578 (Published 11 April 2019) Cite this as: BMJ 2019;365:l1578

Basal cell carcinoma in survivors of childhood cancer

People treated with radiotherapy for a childhood cancer have a 30 fold increased risk of basal cell carcinoma according to a large follow-up study from the Netherlands (J Nat Cancer Inst doi:10.1093/jnci/djy212). The cumulative incidence of this skin cancer in the 40  years after radiotherapy reached 19%—compared with less than 1% in the general population. Rates of melanoma and squamous cell cancer were also increased, but to a lesser extent, and the absolute risk of these cancers was much lower than for basal cell carcinoma.

Treatment and prevention of delirium

A meta-analysis of 58 randomised clinical trials with a total of nearly 10000 participants concludes that the …

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