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Stress related disorders and risk of cardiovascular disease: population based, sibling controlled cohort study

BMJ 2019; 365 doi: https://doi.org/10.1136/bmj.l1255 (Published 10 April 2019) Cite this as: BMJ 2019;365:l1255

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Stress, psychiatric disorders, and cardiovascular disease

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Twice as many women Re: Stress related disorders and risk of cardiovascular disease: population based, sibling controlled cohort study

The conclusion of population based, sibling-controlled cohort study by Huan Song and colleagues is that stress related disorders are robustly associated with multiple types of cardiovascular disease, independently of familial background, history of somatic/psychiatric diseases, and psychiatric comorbidity.

However, in their study almost twice as many people exposed to stress related disorders were women (63%) while their unaffected siblings had an equal sex distribution.1

Further studies should include information on smoking, alcohol use, weight gain, use of contraceptive or HRT progestogens and/or oestrogens and the use of antidepressant or anxiolytic medications which are all known to increase the risk of cardiovascular diseases.

1 Song H, Fang F, Arnberg FK, Mataix-Cols D, et al. Stress related disorders and risk of cardiovascular disease: population based, sibling controlled cohort study. BMJ 2019; 365 doi: https://doi.org/10.1136/bmj.l1255 (Published 10 April 2019) Cite this as: BMJ 2019;365:l1255

Competing interests: No competing interests

11 April 2019
Ellen C G Grant
Physician and medical gynaecologist
Retired
Kingston-upon-Thames, Surrey