Role of maternal age and pregnancy history in risk of miscarriage: prospective register based studyBMJ 2019; 364 doi: https://doi.org/10.1136/bmj.l869 (Published 20 March 2019) Cite this as: BMJ 2019;364:l869
All rapid responses
The best preconception care Re: Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study
The best preconception care
Magnus and colleagues have found that the risk of recurrent miscarriage increases with maternal age and is also increased after some adverse pregnancy outcomes. They think that miscarriage and other pregnancy complications might share underlying causes, which could be biological conditions or unmeasured common risk factors.1
In my experience over decades of investigating and treating couples with "so called" unexplained infertility and recurrent miscarriages, such women are likely to have taken hormonal contraception from young ages. They usually had numerous biochemical abnormalities and often undiagnosed and therefore untreated infections such as endocervical mycoplasma or gut candida.
The best preconception care is necessary for the health of mothers and their children. It involves monitored supplementation of nutrient deficiencies along with a stone age high protein, low allergy diet and the avoidance of alcohol, smoking or drugs (including unnecessary medications). 2-8
The commonest essential nutrient deficiencies are of zinc (white cell), magnesium (red cell), chromium, selenium, copper, B vitamins and essential fatty acids and the commonest toxic DNA adducts are with nickel which block hormone receptors.
Please see my lecture slides and bibliography on my website harmfromhormones.co.uk
1 Magnus MC, Wilcox AJ, Morken N-H, Clarice R Weinberg CR,Haberg SE. Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study. BMJ 2019; 364 doi: https://doi.org/10.1136/bmj.l869 (Published 20 March 2019) Cite this as: BMJ 2019;364:l869.
2 Grant ECG. The harmful effects of common social habits, especially smoking and using oral contraceptive steroids, on pregnancy. Int J Environ Studies 1981;17:57-66.
3 Grant ECG. Recent advances in understanding toxic and teratogenic effects of hormones. The Next Generation: Avoiding damage before birth in the 1980s. Foresight 1983.
4 Barnes B, Grant ECG et al. Nutrition and preconception care. Lancet 1985;2:1297
5 Grant ECG, Howard JM, Davies S, Chasty H, Hornsby B, Galbraith J. Zinc deficiency in children with dyslexia: concentrations of zinc and other minerals in sweat and hair. BMJ 1989;296:607-609.
6 Grant ECG. The declining health of the pill generations. J Nutr Med 1994;4:283-286.
7 Ward N. Preconceptional care and pregnancy outcome. J Nutr Med 1995;5:205-206.
8 Grant ECG. The pill, hormone replacement therapy, vascular and mood over-reactivity and mineral imbalance. J Nutr Environ Med 1998;8:105-116.
Competing interests: No competing interests