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Dutch hospital gets €5m from lottery to develop drug for rare condition after price hike

BMJ 2019; 364 doi: https://doi.org/10.1136/bmj.l732 (Published 14 February 2019) Cite this as: BMJ 2019;364:l732
  1. Tony Sheldon
  1. Utrecht

A Dutch university hospital has been awarded €5m (£4.4m; $5.6m) of lottery funding to help develop its plans to supply its own cost price version of the orphan drug chenodeoxycholic acid (CDCA).

Last year Amsterdam University Medical Center began work on a small scale magistral preparation of CDCA—a primary bile acid used in treating a rare hereditary metabolic disorder, cerebrotendinous xanthomatosis (CTX). This followed health insurers’ refusal to meet the more than fivefold price increase, from €30 000 to around …

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