Intended for healthcare professionals

Letters Hormone replacement therapy and venous thromboembolism

Hormone replacement therapy: transgender studies show safety of estradiol

BMJ 2019; 364 doi: (Published 11 February 2019) Cite this as: BMJ 2019;364:l600
  1. Richard Quinton, consultant and senior lecturer in endocrinology1,
  2. Du Soon Swee, consultant endocrinologist2
  1. 1Endocrine Unit, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
  2. 2Singapore General Hospital, Singapore 169608
  1. richard.quinton{at}

Vinogradova and colleagues show that treating postmenopausal female hypogonadism with an equine xenohormone, rather than physiological estradiol, is associated with a significantly greater risk of venous thromboembolism. …

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