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Intensive BP control reduces mild cognitive impairment but not dementia, study finds

BMJ 2019; 364 doi: https://doi.org/10.1136/bmj.l425 (Published 28 January 2019) Cite this as: BMJ 2019;364:l425
  1. Susan Mayor
  1. London

Intensive blood pressure (BP) control in healthy older adults with hypertension significantly reduces the risk of mild cognitive impairment but not dementia, a large randomised US study has shown.1 Study participants are now being followed up for any reductions in dementia.

Hypertension has previously been identified in observational studies as a potentially modifiable risk factor for mild cognitive impairment and dementia. But randomised trials of intensive BP lowering have been inconclusive, and some observational studies have suggested a link between low BP and a higher risk of cognitive impairment.

Intensive BP control

The Systolic Blood Pressure Intervention Trial (SPRINT) randomly allocated 9361 adults aged over 50 with hypertension …

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