Intensive BP control reduces mild cognitive impairment but not dementia, study findsBMJ 2019; 364 doi: https://doi.org/10.1136/bmj.l425 (Published 28 January 2019) Cite this as: BMJ 2019;364:l425
- Susan Mayor
Intensive blood pressure (BP) control in healthy older adults with hypertension significantly reduces the risk of mild cognitive impairment but not dementia, a large randomised US study has shown.1 Study participants are now being followed up for any reductions in dementia.
Hypertension has previously been identified in observational studies as a potentially modifiable risk factor for mild cognitive impairment and dementia. But randomised trials of intensive BP lowering have been inconclusive, and some observational studies have suggested a link between low BP and a higher risk of cognitive impairment.
Intensive BP control
The Systolic Blood Pressure Intervention Trial (SPRINT) randomly allocated 9361 adults aged over 50 with hypertension …