Research
Enterovirus as trigger of coeliac disease: nested case-control study within prospective birth cohort
BMJ 2019; 364 doi: https://doi.org/10.1136/bmj.l231 (Published 13 February 2019) Cite this as: BMJ 2019;364:l231Linked Editorial
Searching for the missing link in coeliac disease
Re: Enterovirus as trigger of coeliac disease: nested case-control study within prospective birth cohort
This study sometimes confirms an association between Coeliac disease and Entero-virus. No causation has been identified. One can hypothesise about causation but that is all one can do until distinct confirmation of causation can be found. Not ALL patients who went on to develop Coeliac disease were positive for Entero-virus which is a very common pathogen in children.
Would the study be described as under-powered? Could it be reproduced in other populations on different continents at risk of Coeliac disease.
Does this study provide us with any significantly new information as to Entero-virus in the causation of Coeliac disease?
I would prefer to leave that up to the readers to make their own informed decisions.
Competing interests: No competing interests