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Overcoming vaccine hesitancy: five minutes with . . . Heidi Larson

BMJ 2019; 364 doi: https://doi.org/10.1136/bmj.l1259 (Published 18 March 2019) Cite this as: BMJ 2019;364:l1259

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Re: Overcoming vaccine hesitancy: five minutes with . . . Heidi Larson: How would we detect neurological complications?

Thank you Dr Anand [1] for these interesting quotations. I note:

"British National Formulary. Number 10 ( 1985)
Page 384 . Section 14.4.6 , continued on to page 385.%
Serious neurological complications following the vaccine are extremely rare, perhaps of the order of 1 in 87,000 vaccinees snd probably 10-20 times less common than such complications associated with natural infections of measles. but it is difficult to get exact figures because of variable criteria of what is diagnosed as a serious neurological condition."

Of course, this is just for the old measles vaccine. But the question is if children had a serious adverse reaction to MMR followed by neurological complications how would this be picked up by current monitoring systems in the United Kingdom [2,3,4,5]? Can anyone elucidate?

[1] JK Anand, 'Re: Overcoming vaccine hesitancy: five minutes with . . . Heidi Larson', 2 April 2019, https://www.bmj.com/content/364/bmj.l1259/rr-8

[2] Wendy E Stephen, 'Re: A tale of two vaccines: A Tale Of Two Adverse Reaction Reporting Systems' 12 October 2018, https://www.bmj.com/content/363/bmj.k4152/rr-16

[3] Mr Clifford G Miller, 'Re: A tale of two vaccines - MHRA Published Incomplete ADR Data' 14 October, 2018, https://www.bmj.com/content/363/bmj.k4152/rr-18

[4] Clifford G Miller, 'Re: A tale of two vaccines - MHRA - 6 Reports of "rare" suspected ADR in 60 days ignored', 18 October 2018, https://www.bmj.com/content/363/bmj.k4152/rr-21

[5] Clifford G Miller, 'Re: A tale of two vaccines - MHRA Had 178 Pandemrix Altered Consciousness Adverse Event Reports in 67 Days', 23 October 2018, https://www.bmj.com/content/363/bmj.k4152/rr-23

Competing interests: No competing interests

03 April 2019
John Stone
UK Editor
London N22