Intended for healthcare professionals

Letters Fracture risk

Authors’ reply to Sugiyama

BMJ 2019; 364 doi: https://doi.org/10.1136/bmj.l115 (Published 14 January 2019) Cite this as: BMJ 2019;364:l115
  1. Fernando Rivadeneira, associate professor1,
  2. Katerina Trajanoska, PhD student1,
  3. John Morris, PhD student2,
  4. J Brent Richards, professor2
  1. 1Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands
  2. 2McGill University, Montréal, Québec, Canada
  1. f.rivadeneira{at}erasmusmc.nl

A large body of data from randomised clinical trials and large meta-analyses has shown no clear evidence for a beneficial effect of vitamin D on bone mineral density or fracture risk.1 Notably, recent studies have shown that high vitamin D concentrations (above the physiological requirements) can have a deleterious effect on bone health.23 Furthermore, …

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