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Negative pressure dressings are no better than standard dressings for open fractures

BMJ 2019; 364 doi: (Published 13 March 2019) Cite this as: BMJ 2019;364:k4411


NIHR’s research signals in The BMJ

  1. Rob Cook1,
  2. Vaughan Thomas2,
  3. Rosie Martin1
  4. on behalf of the NIHR Dissemination Centre
  1. 1Bazian, Economist Intelligence Unit healthcare, London, UK
  2. 2Wessex Institute, University of Southampton, Southampton, UK
  1. Correspondence to R Cook rob.cook{at}

The study

Effect of negative pressure wound therapy vs standard wound management on 12-month disability among adults with severe open fracture of the lower limb: the WOLLF randomised clinical trial.

Costa ML, Achten J, Bruce J, et al; UK WOLLF Collaboration

Published on 9 October 2018 JAMA 2018;319:2280-8.

This project was funded by the National Institute for Health Research Health Technology Assessment Programme (project number 10/57/20).

To read the full NIHR Signal, go to:


  • Competing interestsThe BMJ has judged that there are no disqualifying financial ties to commercial companies. The authors declare the following other interests: none.

  • Further details of The BMJ policy on financial interests are here:

  • Contributors All authors contributed to development and review of this summary, as part of the wider NIHR Signals editorial team ( RC is guarantor.

  • Disclaimer NIHR Signals are owned by the Department of Health and Social Care and are made available to the BMJ under licence. NIHR Signals report and comment on health and social care research but do not offer any endorsement of the research. The NIHR assumes no responsibility or liability arising from any error or omission or from the use of any information contained in NIHR Signals.

  • Permission to reuse these articles should be directed to disseminationcentre{at}

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