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Statins for primary prevention of cardiovascular events and mortality in old and very old adults with and without type 2 diabetes: retrospective cohort study

BMJ 2018; 362 doi: https://doi.org/10.1136/bmj.k3359 (Published 05 September 2018) Cite this as: BMJ 2018;362:k3359

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Primary prevention with statins for older adults

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Re: Statins for primary prevention of cardiovascular events and mortality in old and very old adults with and without type 2 diabetes: retrospective cohort study

From 2015, a published systematic review demonstrated that high LDL-C is inversely associated with mortality in people over 60 years.
Administering statins in old people in order to decrease LDL-C can actually decrease their survival.
One wonders why ethical approval was obtained from the "local ethics committee" and if all 46,864 patients involved in this cohort study were adequately informed on lowering LDL-C risks before signing consent forms.
Reference
https://bmjopen.bmj.com/content/6/6/e010401

Competing interests: No competing interests

08 September 2018
Stavros Saripanidis
Consultant in Obstetrics and Gynaecology
Thessaloniki, Greece