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Mucosal neuromas of tongue and lips: a diagnostic clue to MEN2B

BMJ 2018; 362 doi: (Published 03 August 2018) Cite this as: BMJ 2018;362:k2906
  1. Rami Alrezk, clinical fellow1,
  2. John Glod, principal investigator2,
  3. Karel Pacak, principal investigator3
  1. 1National Institutes of Health, Neuroendocrinology, Bethesda, MD, USA
  2. 2National Institutes of Health, National Cancer Institute, Bethesda, MD, USA
  3. 3The Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA
  1. Correspondence to R Alrezk ramialrezk1{at}

A 19 year old man with multiple endocrine neoplasia type 2 (MEN2B) presented for follow-up at the endocrine clinic.

The patient had a characteristic MEN2B phenotype; tongue lesions (fig 1), tall stature, …

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