Intended for healthcare professionals


Epilepsy and drug resistance . . . and other stories

BMJ 2018; 362 doi: (Published 05 July 2018) Cite this as: BMJ 2018;362:k2858

Re: Epilepsy and drug resistance . . . and other stories

Drug Resistance Epilepsy in Indian Children

Pharmacoresistance in epileptic children does not necessarily mean that standard antepileptic drugs will not work.

 There are other causes, including noncompliance with drug treatment, seizures that are not organic epileptic, misdiagnosis of the seizure type or epilepsy syndrome, inappropriate use of medications such as inadequate doses or drug-drug interactions. Also, lifestyle issues such as alcohol, drug abuse, stress, and sleep deprivation can also lead to drug resistance in epileptic children.

Poor socioeconomic status, misconceptions, native traditional methods of treatment, neglect of female and differently able children with epilepsy are also reasons for drug resistance epilepsy in Indian children

Competing interests: No competing interests

08 July 2018
M.A. Aleem
Emeritus Professor* Neurologist**
Tamilnadu Dr.M G.R.Medical university* ABC Hospital**
Chennai* Trichy** 620018 Tamilnadu India