Epilepsy and drug resistance . . . and other storiesBMJ 2018; 362 doi: https://doi.org/10.1136/bmj.k2858 (Published 05 July 2018) Cite this as: BMJ 2018;362:k2858
Around 60% of children who develop epilepsy achieve freedom from seizures with drug treatment, according to a population based study of children born from 1999 to 2009 in Norway (Am Acad Pediatr doi:10.1542/peds.2017-4016). On the other hand, about 30% have drug resistant epilepsy, defined as seizures within the last year of follow-up, despite trials of at least two antiepileptic drugs. Having an identified cause of epilepsy, whether structural, genetic, metabolic, or infectious, made drug resistance more likely. These figures aren’t very different from earlier studies of the outcomes of epilepsy in childhood.
Recreating the original data
Given the …