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Clinical Review State of the Art Review

Autism spectrum disorder: advances in diagnosis and evaluation

BMJ 2018; 361 doi: https://doi.org/10.1136/bmj.k1674 (Published 21 May 2018) Cite this as: BMJ 2018;361:k1674

Re: Autism spectrum disorder: advances in diagnosis and evaluation

In answer to John Stone, when I say "muscle meats", I am also referring to fish and poultry. These days, they too are generally eaten without the bones (that used to be tossed into the soup pot instead of the trash), not to mention the likes of shrimp, crab and lobster, of which also only the muscle meats are consumed. And although the consumption of bone broth has now gained some popularity, I think the general shift away from eating it in recent generations is common knowledge. Certainly the overall consumption of meats, fish (including shellfish) and poultry is much higher now in the Western world than in previous generations, and the fact that this results in the depletion of glycine specifically has now been clearly demonstrated in the EPIC-Oxford cohort (1) as I pointed out in my previous response in this string. Perhaps it is unfortunate that those cohort members who consume an omnivorous diet were classified as "meat-eaters", in order to contrast their dietary habits to those who consume no meat or poultry (classified as "fish-eaters"), those who consume no meat, fish or poultry (classified as "vegetarians"), and those who consume no animal products at all ("vegans").

Schmidt JA, Rinaldi S, Scalbert A, et al. Plasma concentrations and intakes of amino acids in male meat-eaters, fish-eaters, vegetarians and vegans: a cross-sectional analysis in the EPIC-Oxford cohort. Eur J Clin Nutrition 2016;70:306–12. doi:10.1038/ejcn.2015.144

Competing interests: No competing interests

11 June 2018
Joel Brind
Professor
Baruch College, City University of New York
1 Bernard Baruch Way, New York, NY 10010 USA