Intended for healthcare professionals

Letters Folic acid fortification

Folic acid and vitamin B12 fortification of food for preventing neural tube defects in Europe

BMJ 2018; 361 doi: (Published 06 April 2018) Cite this as: BMJ 2018;361:k1572
  1. Michael Turner, professor of obstetrics and gynaecology
  1. UCD Centre for Human Reproduction, Coombe Women and Infants University Hospital, Dublin 8, Republic of Ireland
  1. michael.turner{at}

Both sides in the debate on mandatory folate food fortification agree that it would reduce the incidence of neural tube defects and improve population rates of folate deficiency.1

Reynolds, however, argues that it should be accompanied by mandatory vitamin B12 fortification to protect elderly people from neurological dysfunction. National audits in the Republic of Ireland during 2009-11 and 2012-15 found no improvement in rates of neural tube defects with a …

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