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Baclofen is largely ineffective for alcohol use disorders, finds study

BMJ 2018; 360 doi: (Published 26 February 2018) Cite this as: BMJ 2018;360:k930
  1. Susan Mayor
  1. London

Baclofen is largely ineffective for treating alcohol use disorders, a meta-analysis of randomised trials has found.

“This new meta-analysis shows that baclofen is no more effective than placebo on a range of key outcome measures, suggesting that the current increasing use of baclofen as a treatment for alcohol use disorders is premature,” said coauthor Andy Jones, from the University of Liverpool.

Treatment of alcohol use disorders is challenging, with current treatments having high relapse rates of up to 70% within six months. The UK National Institute for Health …

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