Intended for healthcare professionals


Pulmonary function and uric acid . . . and other stories

BMJ 2018; 360 doi: (Published 11 January 2018) Cite this as: BMJ 2018;360:k28

Uric acid and the lungs

Uric acid has antioxidant properties, and Danish investigators wondered if it might protect against impaired pulmonary function. In fact, the reverse seemed to be true since, in two longitudinal studies in Copenhagen, people with high plasma urate levels tended to have poorer lung function and more respiratory symptoms. However, genotyping of participants showed that genetic variants known to be linked to high plasma urate levels were not associated with respiratory outcomes, which suggests that there is no causal relation operating in either direction (Thorax doi:10.1136/thoraxjnl-2017-21027).

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