Intended for healthcare professionals

Rapid response to:

Feature Type 2 Diabetes

Low calorie and low carb diets for weight loss in primary care

BMJ 2018; 360 doi: https://doi.org/10.1136/bmj.k1122 (Published 13 March 2018) Cite this as: BMJ 2018;360:k1122

Rapid Response:

Re: Low calorie and low carb diets for weight loss in primary care

At long last the practical implementation of programmes to control energy/calorific intake. However, this has to be complemented by a programme which increases energy expenditure. The function of exercise is to expel carbon dioxide and thereby reduce intercellular acidity. This is important because increased intercellular acidity reduces the prevailing levels of essential minerals which are indispensable in this process.

Increased intercellular acidity reduces the prevailing levels of magnesium, zinc and chromium. Magnesium is necessary for the reaction of insulin with its receptor protein; zinc is necessary to store insulin; and chromium is necessary for the reaction of GLUT-4 protein in the smooth muscle and hence the generation of energy.

Accordingly there are two options: (i) to control energy intake and energy expenditure; (ii) understand how to stimulate the brain to mimic or stimulate these processes involving the control of appetite, satedness; regulation of intercellular pH; regulation of blood glucose; etc.

Competing interests: No competing interests

19 March 2018
Graham W Ewing
Managing Director
Mimex Montague Healthcare Limited
Mulberry House, 6 Vine Farm Close, Cotgrave, Notts NG12 3TU